For an extra layer of flavor, consider adding a sprinkle of garlic powder or onion powder to the chicken mixture. You can substitute the cream of chicken soup with cream of mushroom or celery soup for a different taste profile. Feel free to use leftover rotisserie chicken to save time. If you don't have sour cream, plain Greek yogurt works as a good substitute. For a spicier kick, add a pinch of red pepper flakes to the chicken mixture. Make sure the biscuits are not overlapping so that they cook evenly.
Melanie's Chicken Biscuits Casserole
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PREP TIME15 mins
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COOK TIME40 mins
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TOTAL TIME55 mins
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SERVING8 People
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VIEWS45
A comforting and hearty casserole that transforms simple ingredients into a satisfying family meal. Tender chicken, a creamy sauce, and golden-brown biscuits combine for a dish that's both easy to make and delightful to eat. Perfect for a weeknight dinner or a potluck gathering!
Ingridients
Adjust Servings
Nutrition
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Carbohydrate21 g
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Cholesterol89 mg
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Fiber0 g
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Protein26 g
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Saturated Fat12 g
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Sodium761 mg
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Sugar4 g
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Fat28 g
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Unsaturated Fat0 g
DIRECTIONS
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01 Step
Recipe View 5 mins Preheat oven to 350 degrees F (175 degrees C). Grease a 9x13-inch baking dish with 1.5 teaspoons of butter. (Prep time: 5 minutes)
02 Step
Recipe View 10 mins In a large bowl, combine the cooked chicken, sour cream, chopped onion, cream of chicken soup, and milk. Mix well to ensure all ingredients are evenly distributed. (Prep time: 10 minutes)
03 Step
Recipe View 2 mins Pour the chicken mixture into the prepared baking dish. (Prep time: 2 minutes)
04 Step
Recipe View 15 mins Bake in the preheated oven until the chicken mixture is heated through, approximately 15 minutes. (Bake time: 15 minutes)
05 Step
Recipe View 8 mins Remove the casserole from the oven. Stir 1/2 cup of shredded Cheddar cheese into the chicken mixture. Arrange the unbaked biscuits evenly over the top of the casserole. Sprinkle the remaining 1/2 cup of Cheddar cheese over the biscuits. (Prep time: 8 minutes)
06 Step
Recipe View 27 mins Return the casserole to the oven and bake until the biscuits are golden brown and cooked through in the middle, and the chicken mixture is bubbling, approximately 25 to 30 more minutes. (Bake time: 25-30 minutes)
07 Step
Recipe View Let the casserole cool for a few minutes before serving. Enjoy!
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Jaqueline Lakin
Jun 30, 2025Easy to follow and tasted great!
Efren Hessel
May 31, 2025The biscuits came out perfectly golden and fluffy. I'll definitely be making this again!
Armando Deckow
Feb 20, 2025I used gluten-free biscuits and it worked perfectly for my dietary needs.
Selina Frami
Jan 4, 2025I added some mixed vegetables to the chicken mixture for extra nutrients. It was delicious!
Alejandrin Cronin
Nov 23, 2024This recipe was a lifesaver on a busy weeknight! My family loved it!